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Transglutaminase Function in Epidermis

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2005Publisher:Elsevier BVJournal:Journal of Investigative Dermatology, volume 124, pages 481-492 (issn: 0022-202X, Copyright policy )
Authors: Monica Ruse; Michael T. Sturniolo; Ellen A. Rorke; Richard L. Eckert; Ann-Marie Broome;

doi: 10.1111/j.0022-202x.2005.23627.x

pmid: 15737187

Transglutaminase Function in Epidermis

Abstract

Surface epithelial cells, such as the epidermal keratinocyte, undergo a process of terminal cell differentiation that results in the construction of a multilayered epithelium. This epithelium functions to protect the organism from the environment. Transglutaminases, enzymes that catalyze the formation of isopeptide protein-protein cross-links, are key enzymes involved in the construction of this structure. This brief review will focus on the role of these enzymes in constructing the epidermal surface.

Related Organizations
Keywords

Keratinocytes, calcium, Transglutaminases, keratinocyte, differentiation, Cell Biology, Dermatology, Biochemistry, involucrin, transglutaminase, Epidermal Cells, epidermis, Humans, Epidermis, Molecular Biology

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 191
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
191
Top 1%
Top 10%
Top 10%
hybrid