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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Internal Medicine Jo...arrow_drop_down
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Internal Medicine Journal
Article . 2018 . Peer-reviewed
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Comorbidity in psoriatic arthritis and rheumatoid arthritis

Authors: Premarani Sinnathurai; Rachelle Buchbinder; Catherine Hill; Marissa Lassere; Lyn March;

Comorbidity in psoriatic arthritis and rheumatoid arthritis

Abstract

AbstractBackgroundComorbid conditions are common and impact outcomes in people with rheumatoid arthritis (RA), but less data are available for psoriatic arthritis (PsA).AimsTo describe baseline demographics and prevalence of comorbidities in participants with PsA in an Australian cohort using data from the Australian Rheumatology Association Database (ARAD) and to compare the prevalence of comorbidities in ARAD participants with PsA with those with RA.MethodsARAD is a voluntary national registry for inflammatory arthritis. Data, including demographic details, medication use, history of comorbid medical illnesses and patient‐reported outcomes, all self‐reported, were extracted from questionnaires completed at the time of database enrolment for participants with PsA and RA. Demographic information and prevalence of comorbidities were summarised using descriptive statistics. Prevalence of comorbidities in PsA and RA were compared using logistic regression, adjusting for age, gender, disease duration, education, employment and prednisone use.ResultsThere were 490 participants with PsA, 59.2% female, mean (standard deviation (SD)) age 50.4 (21.1) years and disease duration 16.4 (9.7) years, and 57.8% reported having two or more comorbidities. Hypertension (38.2%) and depression (35.9%) were the most common. Compared with RA, participants with PsA had greater odds of depression (adjusted OR (95% CI): 2.1 (1.7–2.6)), hypertension (1.7 (1.4–2.1)), hyperlipidaemia (2.0 (1.6–2.5)), diabetes (2.2 (1.6–3.0)) and a history of ischaemic heart disease (2.0 (1.3–2.9)).ConclusionsHigh rates of comorbidity were found in ARAD participants with PsA. The prevalence of depression, cardiovascular risk factors and other comorbidities were higher in PsA than RA participants in our Australian cohort.

Keywords

Adult, Male, rheumatoid, 610, Comorbidity, Arthritis, Rheumatoid, cardiovascular disease, Risk Factors, Neoplasms, Surveys and Questionnaires, Humans, Longitudinal Studies, Registries, Aged, Depression, Arthritis, Arthritis, Psoriatic, Australia, registries, Middle Aged, comorbidity, Cardiovascular Diseases, Antirheumatic Agents, Chronic Disease, Female, psoriatic

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
25
Top 10%
Top 10%
Top 10%
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