Disseminated actinomycetoma due to Nocardia wallacei
Copyright policy )Disseminated actinomycetoma due to Nocardia wallacei
AbstractBackgroundActinomycetoma caused by Nocardia usually responds well to antibiotics. Emerging species of Nocardia, such as N. wallacei, can be a therapeutic challenge.AimsConfirm the therapeutic effectivity of linezolid in multidrug resistant Nocardia Wallacei actinomycetoma.Materials and MethodsWe evaluated the medical management of an 18‐year‐old man with multidrug resistant actinomycetoma of the left leg caused by N. transvalensis complex treated 17 years ago with linezolid 1200 mg a day. This bacteria was recently reclassified as Nocardia Wallacei by specific molecular biology technique.ResultsThe infection was cured after 3 months of treatment; the patient remained asymptomatic for the past 17 years. No adverse effects were found.DiscussionFrequently, strains of N. transvalensis complex have aminoglycoside resistance; in this case, we highlight the effectiveness of linezolid for the successful medical management of multidrug resistant actinomycetoma.ConclusionLinezolid can be an alternative for the treatment of multidrug resistant Nocardia Wallacei.
- The University of Texas System United States
- The University of Texas Health Science Center at Houston United States
- Universidad Autónoma de Nuevo León Mexico
- The University of Texas Health Science Center at Tyler United States
Male, Time Factors, Adolescent, Biopsy, Needle, Nocardia Infections, Microbial Sensitivity Tests, Immunohistochemistry, Amputation, Surgical, Drug Resistance, Multiple, Nocardia, Anti-Bacterial Agents, Treatment Outcome, Lower Extremity, Mycetoma, Disease Progression, Humans, Mexico, Follow-Up Studies
Male, Time Factors, Adolescent, Biopsy, Needle, Nocardia Infections, Microbial Sensitivity Tests, Immunohistochemistry, Amputation, Surgical, Drug Resistance, Multiple, Nocardia, Anti-Bacterial Agents, Treatment Outcome, Lower Extremity, Mycetoma, Disease Progression, Humans, Mexico, Follow-Up Studies
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