Beyond the spike: Functional (dissociative) seizures as a key to holistic attitudes in seizure disorders

descriptionPublicationkeyboard_double_arrow_right Article 23 Sep 2025 English Publisher:WileyJournal:Epilepsia, volume 67, pages 27-32 (issn: 0013-9580, eissn: 1528-1167,

Copyright policy )Funded by:UKRI | Interoception and functio...

Authors: Mahinda Yogarajah; Barbara Dworetzky; Josemir W. Sander; Angel Aledo‐Serrano;

doi: 10.1111/epi.18651

pmid: 40985906

Beyond the spike: Functional (dissociative) seizures as a key to holistic attitudes in seizure disorders

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Abstract

Abstract Epileptologists can improve outcomes through follow‐up and coordination of care for patients with functional seizures. Epileptic and functional seizures share some mechanistic overlap involving interoceptive, emotional, and stress dysregulation, and disorders of agency and perception. Similar psychiatric and neurological comorbidities occur at comparable rates in both functional and epileptic seizure populations. A holistic, biopsychosocial approach benefits all seizure patients and reflects modern models of epilepsy care.

Related Organizations

Brigham and Women's Faulkner Hospital
United States
Complutense University of Madrid
Spain
University College London
United Kingdom
Harvard University
United States
National Institute for Health Research
United Kingdom

Keywords

Epilepsy, Seizures, Commentary, Humans, Dissociative Disorders, Holistic Health

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