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ANZ Journal of Surgery
Article . 2014 . Peer-reviewed
License: Wiley Online Library User Agreement
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Anastomotic leaks in colorectal surgery

Authors: Damen, N.; Spilsbury, Katrina; Levitt, M.; Makin, G.; Salama, P.; Tan, P.; Penter, C.; +1 Authors

Anastomotic leaks in colorectal surgery

Abstract

AbstractBackgroundAnastomotic leaks are a serious complication of bowel surgery. This study aimed to evaluate the rate and severity, and identify risk factors for leaks in patients undergoing bowel anastomoses.MethodsProspective evaluation was performed on patients undergoing bowel surgery within a colorectal surgical unit. Anastomotic leak was defined and graded according to severity. A nurse independently collected the information. Stepwise logistic regression analysis was performed.ResultsTwo thousand three hundred and sixty‐three patients underwent 2994 anastomoses. Their median age was 64 years. Seven per cent were emergency operations. Anastomotic leak occurred in 82 patients (2.7%). Sixty‐three per cent of leaks were managed with drainage or re‐operation. Ultra‐low anterior resection (ULAR) was associated with the highest subgroup leak rate (7.3%). In multivariable analysis, independent predictors for a leak included ‘other’ pathologies (iatrogenic injury, ischaemia, radiation enteritis) (P = 0.016, odds ratio (OR): 6.3, 95% confidence interval (CI): 1.4–28.0), ULAR (P = 0.001, OR: 8.5, 95% CI: 2.3–31.2) and the surgeon (A: P < 0.001, OR: 3.4, 95% CI: 2.1–5.6).ConclusionMajority of predictors for anastomotic leak were fairly intuitive. Nonetheless, it was relevant to note the importance of the individual surgeon as an independent predictor for leaks.

Country
Australia
Keywords

Adult, Male, Reoperation, anastomotic leak, 610, Anastomotic Leak, inflammatory bowel diseases, Severity of Illness Index, intestinal neoplasm, Risk Factors, 617, Humans, Prospective Studies, effect modifier, Aged, Aged, 80 and over, Incidence, Middle Aged, Treatment Outcome, colorectal surgery, Female, Colorectal Surgery, New Zealand

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
51
Top 10%
Top 10%
Top 10%
bronze