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Journal of Investigative Dermatology
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Journal of Investigative Dermatology
Article . 1978
License: Elsevier Non-Commercial
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http://dx.doi.org/10.1111/1523...
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Journal of Investigative Dermatology
Article . 1978 . Peer-reviewed
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Journal of Investigative Dermatology
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Identification of Topical Photosensitizing Agents in Humans

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1978 English Publisher:Elsevier BVJournal:Journal of Investigative Dermatology, volume 70, pages 149-151 (issn: 0022-202X, Copyright policy )
Authors: Kays H. Kaidbey; Albert M. Kligman;

doi: 10.1111/1523-1747.ep12258568

pmid: 632620

Identification of Topical Photosensitizing Agents in Humans

Abstract

A method is described for the detection of topical photosensitizers in humans. Test agents were applied to the untanned midback under an occlusive dressing for 6 hr and then exposed to broad-spectrum radiation containing UV-A and visible wavelengths from a Xenon arc source. Well-known topical photosensitizers were readily identified. It was found that with certain poorly-penetrating substances, such as water-soluble dyes, applications to scarified skin were necessary to reveal phototoxic activity. In addition, these dyes were activated by wavelengths in the visible region of the spectrum.

Related Organizations
Keywords

Adult, Ultraviolet Rays, Administration, Topical, Cell Biology, Dermatology, Cosmetics, Biochemistry, Perfume, Phenols, Methods, Humans, Photosensitivity Disorders, Coloring Agents, Molecular Biology, Skin

  • BIP!
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 58
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
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    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
58
Top 10%
Top 10%
Top 10%
hybrid