
pmid: 15376516
We introduce a new optical method to noninvasively and continuously measure the swelling process of the nasal mucosa whereby we use light of different wavelengths in the red and near-infrared range which is transilluminated through the nasal tissue and whose extinction is recorded as a function of time. From the temporal and spectral extinction data, we are able to extract characteristic parameters that describe the swelling process quantitatively by means of a regression-type parameter estimation algorithm. The method has been applied to the nasal allergen provocation test and verified on a limited number of volunteers.
allergy diagnostics, Adult, Male, Optics and Photonics, Nasal Provocation Tests, Spectrophotometry, Infrared, Transducers, NIR spectroscopy, Reproducibility of Results, Equipment Design, Middle Aged, Sensitivity and Specificity, Equipment Failure Analysis, Nasal Mucosa, nasal provocation test, Nose Diseases, Edema, Humans, Female, Diagnosis, Computer-Assisted, optical sensor
allergy diagnostics, Adult, Male, Optics and Photonics, Nasal Provocation Tests, Spectrophotometry, Infrared, Transducers, NIR spectroscopy, Reproducibility of Results, Equipment Design, Middle Aged, Sensitivity and Specificity, Equipment Failure Analysis, Nasal Mucosa, nasal provocation test, Nose Diseases, Edema, Humans, Female, Diagnosis, Computer-Assisted, optical sensor
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