Equilibrium Binding in Immunosensors

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1986Publisher:Institute of Electrical and Electronics Engineers (IEEE)Journal:IEEE Transactions on Biomedical Engineering, volume BME-33, pages 133-138 (issn: 0018-9294,

Copyright policy )

Authors: B L, Liu; J S, Schultz;

doi: 10.1109/tbme.1986.325887

pmid: 3957364

Equilibrium Binding in Immunosensors

- Summary
- Subjects
- Metrics

Abstract

An in vitro solid-phase immunoassay system was studied in order to characterize immunosensor binding reactions. Several variables were explored, including the spacing of immobilized antibodies and the size and valence of analyte analogs. Under appropriate conditions, binding enhancement was observed, suggesting that the chemistry of the system can be experimentally controlled in order to meet specified criteria for sensitivity and other characteristics of the biosensor.

Related Organizations

University of Michigan–Flint
United States
Eli Lilly (United States)
United States
University of Michigan–Ann Arbor
United States

Keywords

Immunoassay, Kinetics, Humans, Binding, Competitive, Blood Chemical Analysis, Fluorescence

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	20
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%