The arrival of genetic engineering
Copyright policy )The arrival of genetic engineering
The purpose of this article is to review the different strategies for the delivery of plasmid DNA (pDNA)-based gene therapy. Plasmids are extrachromosomal DNA capable of being transmitted from cell to cell. They are supercoiled, circular covalently closed (ccc) strands of DNA capable of replication independently of host DNA and ranging from 5 to 400 kilo base pairs (kb) in size, depending on the size of the therapeutic gene insert.
- University College London United Kingdom
- Loughborough University United Kingdom
- University of Galway Ireland
Peptide Nucleic Acids, Magnetics, Cystic Fibrosis, Drug Administration Routes, Nebulizers and Vaporizers, Gene Transfer Techniques, Humans, Genetic Therapy, Metered Dose Inhalers, Plasmids
Peptide Nucleic Acids, Magnetics, Cystic Fibrosis, Drug Administration Routes, Nebulizers and Vaporizers, Gene Transfer Techniques, Humans, Genetic Therapy, Metered Dose Inhalers, Plasmids
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