In recent years, telecom operators have been moving away from traditional, broadcast-driven, television towards IP-based, interactive and on-demand services. Consequently, multicast is no longer a viable solution to limit the amount of traffic in the IP-TV network. In order to counter an explosion in generated traffic, caches can be strategically placed throughout the content delivery infrastructure. As the size of caches is usually limited to only a small fraction of the total size of all content items, it is important to accurately predict future content popularity. Classical caching strategies only take into account the past when deciding what content to cache. Recently, a trend towards novel strategies that actually try to predict future content popularity has arisen. In this paper, we ascertain the viability of using popularity prediction in realistic multimedia content caching scenarios. The use of popularity prediction is compared to classical strategies using trace files from an actual deployed Video on Demand service. Additionally, the synergy between several parameters, such as cache size and prediction window, is investigated.