Since birth the first and the most natural interface for the body is fabric, a soft, warm and reassuring material. Cloth is usually covering more than 80 % of the skin; which leads us to consider textile material as the most appropriate interface where new sensorial and interactive functions can be implemented. The new generation of personalised monitoring systems is based on this paradigm: functions like sensing, transmission and elaboration are implementable in the materials through the textile technology. Functional yarns and fibres are usable to realise garments where electrical and computing properties are combined with the traditional mechanical characteristics, giving rise to textile platforms that are comparable with the cloths that are normally used to produce our garments. The feel of the fabric is the same, but the functionality is augmented. Nowadays, consumers demand user-friendly connectivity and interactivity; sensing clothes are the most natural and ordinary interface able to follow us, everywhere in a non-intrusive way, in natural harmony with our body.