A Computational Model of Rat Cerebral Blood Flow using Non-Uniform Rational B-splines

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2007Publisher:IEEEJournal:2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (issn: 1557-170X,

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Authors: Sergey V, Pushkin; Guennady I, Podoprigora; Laurent, Comas; Hatem, Boulahdour; Jean-Claude, Cardot; Michel, Baud; Yaroslav R, Nartsissov; +1 Authors

doi: 10.1109/iembs.2007.4352487

pmid: 18002153

A Computational Model of Rat Cerebral Blood Flow using Non-Uniform Rational B-splines

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Abstract

Non-Uniform Rational B-splines (NURBS) surfaces can be used for a computer simulation of shapes. Some anatomical models of human or animal structures have been recently developed on that basis. We used positron-emission tomography (PET) and computed tomography (CT) data for NURBS modeling of anatomical structures and isotope uptake in the rat brain. Our simplified model of the rat cerebral blood flow is the first step in a larger project aiming a simulation of PET scans in small animals followed by its validation in vivo.

Related Organizations

UNIVERSITE MARIE ET LOUIS PASTEUR
France
Institute of Cytochemistry and Molecular Pharmacology
Russian Federation
University of Franche-Comté
France

Keywords

Models, Anatomic, Models, Neurological, Models, Cardiovascular, Brain, Numerical Analysis, Computer-Assisted, Rats, Fluorodeoxyglucose F18, Cerebrovascular Circulation, Positron-Emission Tomography, Image Interpretation, Computer-Assisted, Animals, Computer Simulation, Radiopharmaceuticals, Tomography, X-Ray Computed, Algorithms

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