The work outlined in this paper is towards developing a portable, economy blood glucose meter for self-monitoring of blood glucose, which has high performance-price ratio with multifunction and is attractive to the average people. Its functions include blood glucose concentration measurement, LCD display, historical records restore, calendar/timer. It enables the patients with diabetes to detect blood glucose with a glucose oxidase electrode independently at home. This paper will outline hardware configuration in the implementation and software management. Especially, graphic trend curve on LCD allows individuals to easily see how actual blood glucose readings compare with historical records stored in the meter and show how individuals stay within their specific target range so that they can determine how well they are controlling their diabetes. Experimental results indicate that this device is easy-to-use and suitable for home blood glucose monitoring for patients.