Blood velocity measurements in the skin of pigs are reported. Measurements were obtained using laser speckle contrast analysis with a multiple scattering correction. Laser speckle contrast analysis is a rapid technique for obtaining a velocity mapping of perfused tissue. Measurements of blood velocity in pig skin were obtained using a laser and a monochrome digital camera. Blood velocities were measured in tissue prior to and after elevation of flaps. The effect of Iloprost and nitroglycerine on local blood velocity was also examined in nonexcised tissue.