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https://doi.org/10.1109/iembs....
Article . 2005 . Peer-reviewed
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Anodal Block Of Myelinated Nerve Fibers: A Modeling Study

a modeling study
Authors: Holsheimer, Jan; van der Heide, G.G.; Struijk, J.J.;

Anodal Block Of Myelinated Nerve Fibers: A Modeling Study

Abstract

Electrical stimulation of myelinated nerve fibers was analyzed, using point sources in a simple (homogeneous) volume conductor model and a dynamic model of mammalian nerve fiber properties. The stimulus conditions resulting in anodal block of a propagating action potential were calculated as a function of electrode position. Results were compared with those from an analytical approach, using a passive fiber model under steady-state conditions. In comparison to the range of stimulus amplitudes suitable for cathodal nerve fiber recruitment, anodal block appears to be restricted to a small range and - at small electrode distance - to depend on the position relative to nodes of Ranvier.

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    popularity
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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Top 10%
Average