This paper describes an electrooculography (EOG) based human-wheelchair interface for wheelchair users. A pair of electrodes which measures the eye-gaze direction of users is desired as wheelchair manipulation commands. In addition to EOG based wheelchair manipulations, this paper also introduces ultrasonic arrays for detecting distances to actively avoid collisions. In order to simplify setup procedures of using this system, two electrodes are mounted on two side arms of eyeglasses respectively that are possible to have tight contacts with skins around eyes. Therefore, wheelchair movements are capable of following eye-gaze directions. On the other hand, an analog biopotential signal amplifier and a laptop computer are used to develop the proposed EOG based human-wheelchair interface controller. Finally, experimental results demonstrate the operations of EOG based human-wheelchair interface.