Semantic Computing extends Semantic Web both in breadth and depth. It bridges, and integrates, technologies such as software engineering, user interface, natural language processing, artificial intelligence, programming language, grid computing and pervasive computing, among others, into a complete and unified theme. Cloud Computing, the dream of computing as a utility, shifts user programs and data from personal computers to the clouds, providing all kinds of resources over the Internet as services to customers and letting customers pay for them in a way much like they pay for traditional utilities such as electricity. This paper analyzes both Semantic Computing and Cloud Computing, and introduces the Semantic Search Engine, an infrastructure and implementation of Semantic Computing, that demonstrates how Semantic Computing can benefit Cloud Computing.