Intradermal needle-free powdered drug injection by a helium-powered device
Intradermal needle-free powdered drug injection by a helium-powered device
We present a new method for needle-free powdered drug injection via a bench-top gas-powered device. This injector provides an alternative method of vaccine delivery to address the cold chain problem--the cost and risk of transporting temperature sensitive vaccines to developing countries. The device houses interchangeable nozzle inserts to vary orifice geometries and is capable of delivering polymer beads (1-5 µm diameter) into the dermal layer of porcine tissue. Results for injection shape and injection depth versus nozzle orifice diameter demonstrate the device's controllability.
- Massachusetts Institute of Technology United States
Vaccines, Injections, Intradermal, Swine, Vaccination, Equipment Design, Helium, Equipment Failure Analysis, Electric Power Supplies, Needles, Injections, Jet, Animals, Powders
Vaccines, Injections, Intradermal, Swine, Vaccination, Equipment Design, Helium, Equipment Failure Analysis, Electric Power Supplies, Needles, Injections, Jet, Animals, Powders
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