Combinatorial testing methods are often applied in cases of configuration testing. Good practice points to the simultaneous application of combinatorial testing and virtualization. Virtualization, in the process of testing, is based on setting the necessary environment to multiple virtual machines, which run on one computer or in smaller groups of computers, which are: reduce the cost of equipment and related resources, reduce the time required to manage the testing process, and favours raising removal of test infrastructure. Together, combinatorial testing and virtualization presents a practical approach to improving testing process, through the balancing of quality, cost and time.