Hyperparameter optimization is often done manually or by using a grid search. However, recent research has shown that automatic optimization techniques are able to accelerate this optimization process and find hyperparameter configurations that lead to better models. Currently, transferring knowledge from previous experiments to a new experiment is of particular interest because it has been shown that it allows to further improve the hyperparameter optimization. We propose to transfer knowledge by means of an initialization strategy for hyperparameter optimization. In contrast to the current state of the art initialization strategies, our strategy is neither limited to hyperparameter configurations that have been evaluated on previous experiments nor does it need meta-features. The initial hyperparameter configurations are derived by optimizing for a meta-loss formally defined in this paper. This loss depends on the hyperparameter response function of the data sets that were investigated in past experiments. Since this function is unknown and only few observations are given, the meta-loss is not differentiable. We propose to approximate the response function by a differentiable plug-in estimator. Then, we are able to learn the initial hyperparameter configuration sequence by applying gradient-based optimization techniques. Extensive experiments are conducted on two meta-data sets. Our initialization strategy is compared to the state of the art for initialization strategies and further methods that are able to transfer knowledge between data sets. We give empirical evidence that our work provides an improvement over the state of the art.