The airworthiness certification system based on Visual Basic was developed. The system is applicable to safety assessment of airworthiness certification in the initial airworthiness. It works in airworthiness review process as the main line, technical points as the core. The key technologies include the tree maps of all the subsystems, the orders the subsystems should obey, and the safety assessment methods apply to the subsystems. The system contains more than 260 related regulations, 40 tree maps of the subsystems, more than 10 kinds of safety assessment methods, and the number of interface is also above 300. The structure of the system is very clear, simple operation, key technology related requirements and assessment methods to access.