In order to experiment the performance of some popular ANN algorithms to OMIS (Operational Modular Imaging Spectrometer) hyperspectral image, three widely used ANNs, including Back Propagation Neural Network (BPNN), Radial Basis Function Neural Network (RBFNN), Fuzzy ARTMAP network and their improvements, are employed and compared. It is concluded that ANN classifiers perform much better than traditional classifiers such as SAM, MLC and MDC, and RBFNN outperforms BPNN and Fuzzy ARTMAP in terms of classification accuracy. It is also concluded that dimensionality reduction by PCA can be effectively used to feature extraction for hyperspectral image classification.