In this paper, we consider the problem of estimating the state of a dynamical system from distributed noisy measurements. Each agent constructs a local estimate based on its own measurements and estimates from its neighbors. Estimation is performed via a two stage strategy, the first being a Kalman-like measurement update which does not require communication, and the second being an estimate fusion using a consensus matrix. In particular we study the interaction between the consensus matrix, the number of messages exchanged per sampling time, and the Kalman gain. We prove that optimizing the consensus matrix for fastest convergence and using the centralized optimal gain is not necessarily the optimal strategy if the number of message exchange per sampling time is small. Moreover, we prove that under certain conditions the optimal consensus matrix should be doubly stochastic. We also provide some numerical examples to clarify some of the analytical results.