Simultaneous transmit and receive (STAR) systems require high isolation between the transmitter and receiver to avoid self-interference. Antenna isolation degradation stems from errors in the physical construction and beamformer design, as well as reflections from scattering objects in the environment. An RF canceller subsystem can be inserted at the antenna feeds to improve the isolation in the presence of reflecting objects by 30 dB over 30 MHz centered at 2.45 GHz. This results in 90 dB of effective antenna isolation when paired with a high-isolation antenna that exhibits omni-directional radiation patterns, signifying that STAR systems can be practically deployed.