The vehicle dynamics model and desired target tracking model were established. The variable structure controller for active front steering (AFS) and direct yaw moment control (DYC) is designed using sliding mode control (SMC) technique considering the external disturbance and system uncertainty. The step input and sine input simulation results show that the yaw rate and side slip angle of the vehicle with the designed controller can follow that of desired target tracking model. The vehicle handling performance and stability are greatly improved. In the same time the system with designed controller has good robustness to its uncertainty.