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A Machine Learning Framework for Pulse Detection During Out-of-Hospital Cardiac Arrest

Authors: Erik Alonso; Unai Irusta; Elisabete Aramendi; Mohamud R. Daya;

A Machine Learning Framework for Pulse Detection During Out-of-Hospital Cardiac Arrest

Abstract

The availability of an automatic pulse detection during out-of-hospital cardiac arrest (OHCA) would allow the rapid identi cation of cardiac arrest and the prompt detection of return of spontaneous circulation. The aim of this study was to develop a reliable pulse detection algorithm using the electrocardiogram (ECG) and thoracic impedance (TI), the signals available in most de brilators. The dataset used in the study consisted of 1140 ECG and TI segments from 187 OHCA patients, whereof 792 were labelled as pulse-generating rhythm (PR) and 348 as pulseless electrical activity (PEA) by a pool of experts in OHCA. First, an adaptive ltering scheme was used to extract the impedance circulation component and its rst derivative from the TI. Then, the wavelet decomposition of the ECG was carried out to obtain the different subband components and the denoised ECG. Pulse/no-pulse (PR/PEA) discrimination features were extracted from those signals and fed into a support vector machine (SVM) classi er that made the pulse/nopulse decision. A quasi-strati ed and patient wise nested cross validation procedure was used to select the best feature subset and to tune the SVM hyperparameters. This procedure was repeated 50 times to estimate the statistical distributions of the performance metrics of the method. The optimal solution consisted in a ve feature classi er that yielded a mean (standard deviation) sensitivity, speci city, balanced accuracy and total accuracy of 92.4% (0.7), 93.0% (0.8), 92.7% (0.5) and 92.6%(0.5), respectively. When compared to available methods, our solution presented an improvement in balanced accuracy of at least 2.5 points. A reliable pulse detection algorithm for OHCA using the signals available in de brillators was acomplished.

This work was supported in part by the Spanish Ministry of Science, Innovation and Universities, jointly with the Fondo Europeo de Desarrollo Regional (FEDER), under Grant RTI2018-101475-Bl00, and in part by the Basque Government under Grant IT-1229-19.

Country
Spain
Keywords

pulse detection, thoracic impedance, electrocardiogram (ECG), TK1-9971, machine learning, out-of-hospital cardiac arrest (OHCA), Machine learning, adaptive filtering, stationary wavelet transform (SWT), support vector machine (SVM), Electrical engineering. Electronics. Nuclear engineering

  • BIP!
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    9
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
9
Top 10%
Average
Top 10%
Green
gold