The fault tolerant control problem is investigated for a class of uncertain networked control systems (NCSs) subject to actuator faults and actuator saturation in this paper. System parameter uncertainties are considered and a sector condition method is employed to deal with the saturation problem. Based on the network transmission environment, the NCSs can be modeled as a class of saturated discrete-time systems with time-varying delays and actuator faults. By using Lyapunov-Krasovskii (L-K) stability theory, a sufficient condition for the fault tolerant controller design of NCSs is derived in the form of linear matrix inequalities. Finally, simulation results are given to demonstrate the effectiveness of the proposed method.