A new approach of general systems theory is used to study the feasibility of the definition of the theory so‐called the science of science. General scientific theory is studied as a system. The technique, well used by Bertrand Russell in his famous Russell paradox, is applied to show that the theory of science of science cannot exist. A new definition of the theory of science of science is given, so that paradoxes similar to Russell's paradox will not occur in the new theory of science of science developed on the new definition.