New Algorithm for Protein Design
Copyright policy )New Algorithm for Protein Design
We apply a new approach to the reverse protein folding problem. Our method uses a minimization function in the design process which is different from the energy function used for folding. For a lattice model, we show that this new approach produces sequences that are likely to fold into desired structures. Our method is a significant improvement over previous attempts which used the energy function for designing sequences.
10 pages latex 2.09 no figures. Use uufiles to decode
- University of California, Santa Cruz United States
- University of California United States
- University of California United States
- University of California, Los Angeles United States
- University of California, Berkely United States
FOS: Biological sciences, Condensed Matter (cond-mat), FOS: Physical sciences, Condensed Matter, Quantitative Biology (q-bio), Quantitative Biology
FOS: Biological sciences, Condensed Matter (cond-mat), FOS: Physical sciences, Condensed Matter, Quantitative Biology (q-bio), Quantitative Biology
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