In usual quantum theory, the information available about a quantum system is defined in terms of the density matrix describing it on a spacelike surface. This definition must be generalized for extensions of quantum theory which do not have a notion of state on a spacelike surface. It must be generalized for the generalized quantum theories appropriate when spacetime geometry fluctuates quantum mechanically or when geometry is fixed but not foliable by spacelike surfaces. This paper introduces a four-dimensional notion of the information available about a quantum system's boundary conditions in the various sets of decohering histories it may display. The idea of spacetime information is applied in several contexts: When spacetime geometry is fixed the information available through alternatives restricted to a spacetime region is defined. The information available through histories of alternatives of general operators is compared to that obtained from the more limited coarse- grainings of sum-over-histories quantum mechanics. The definition of information is considered in generalized quantum theories. We consider as specific examples time-neutral quantum mechanics with initial and final conditions, quantum theories with non-unitary evolution, and the generalized quantum frameworks appropriate for quantum spacetime. In such theories complete information about a quantum system is not necessarily available on any spacelike surface but must be searched for throughout spacetime. The information loss commonly associated with the ``evolution of pure states into mixed states'' in black hole evaporation is thus not in conflict with the principles of generalized quantum mechanics.

47pages, 2 figures, UCSBTH 94-04