Analyzing Microarray Data

descriptionPublicationkeyboard_double_arrow_right Article 29 Aug 2016 United States English Publisher:Cold Spring Harbor LaboratoryJournal:Cold Spring Harbor Protocols, volume 2,017, page pdb.prot093112 (issn: 1940-3402, eissn: 1559-6095,

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Authors: Hung, Jui-Hung; Weng, Zhiping;

doi: 10.1101/pdb.prot093112

pmid: 27574201

handle: 20.500.14038/25809

Analyzing Microarray Data

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Abstract

Because there is no widely used software for analyzing RNA-seq data that has a graphical user interface, this protocol provides an example of analyzing microarray data using Babelomics. This analysis entails performing quantile normalization and then detecting differentially expressed genes associated with the transgenesis of a human oncogene c-Myc in mice. Finally, hierarchical clustering is performed on the differentially expressed genes using the Cluster program, and the results are visualized using TreeView.

Country

United States

Related Organizations

University of Massachusetts Medical School
United States

Keywords

Mice, Bioinformatics, Sequence Analysis, RNA, Gene Expression Profiling, Computational Biology, Animals, Humans, Microarray Analysis

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