
Abstract Identifying selective sweeps in populations that have complex demographic histories remains a difficult problem in population genetics. We previously introduced a supervised machine learning approach, S/HIC , for finding both hard and soft selective sweeps in genomes on the basis of patterns of genetic variation surrounding a window of the genome. While S/HIC was shown to be both powerful and precise, the utility of S/HIC was limited by the use of phased genomic data as input. In this report we describe a deep learning variant of our method, diploS/HIC , that uses unphased genotypes to accurately classify genomic windows. diploS/HIC is shown to be quite powerful even at moderate to small sample sizes
Recombination, Genetic, Base Sequence, Genotype, Genome, Insect, Deep learning, QH426-470, Investigations, Chromosomes, Machine Learning, ROC Curve, Anopheles, Genetics, Image Processing, Computer-Assisted, Animals, and Population genetics, Neural Networks, Computer, Selective Sweeps, Adaptation, Selection, Genetic
Recombination, Genetic, Base Sequence, Genotype, Genome, Insect, Deep learning, QH426-470, Investigations, Chromosomes, Machine Learning, ROC Curve, Anopheles, Genetics, Image Processing, Computer-Assisted, Animals, and Population genetics, Neural Networks, Computer, Selective Sweeps, Adaptation, Selection, Genetic
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