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AbstractBackground: Tic suppression is the primary target of tic disorder treatment, but factors that influence voluntary tic inhibition are not well understood. Several studies using the Tic Suppression Task have demonstrated significant inter-individual variability in tic suppressibility but have individually been underpowered to address correlates of tic suppression. The present study explored patterns and clinical correlates of tic suppression in youth with tic disorders using a large, pooled dataset.Methods: Individual-level data from 9 studies using the Tic Suppression Task were pooled, yielding a sample of 99 youth with tic disorders. Analyses examined patterns of tic suppressibility and the relationship between tic suppressibility and demographic and clinical characteristics.Results: A large majority of youth demonstrated a high degree of tic suppression, but heterogeneous patterns of tic suppressibility were also observed. Better tic suppressibility was related to older age and more frequent tics but unrelated to other clinical variables, including presence of psychiatric comorbidity, psychotropic medication status, and tic and premonitory urge severity.Conclusions: The mechanisms underlying the observed heterogeneity in tic suppressibility warrant further investigation. The Tic Suppression Task is a promising method for testing mechanistic hypotheses related to tic suppression.
Pediatric, tic, Psychiatry, child, Biomedical and Clinical Sciences, Tourette, Clinical Sciences, 150, Neurosciences, RC435-571, 610, Clinical sciences, Neurodegenerative, suppression, Brain Disorders, adolescent, Public Health and Health Services, Psychology, Mental health, Tourette Syndrome
Pediatric, tic, Psychiatry, child, Biomedical and Clinical Sciences, Tourette, Clinical Sciences, 150, Neurosciences, RC435-571, 610, Clinical sciences, Neurodegenerative, suppression, Brain Disorders, adolescent, Public Health and Health Services, Psychology, Mental health, Tourette Syndrome
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 42 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |