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Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention?

Name: Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention?
Keywords: Adenoma, Adult, Technology, Sulfonamides, Aspirin, Cyclooxygenase 2 Inhibitors, T, Science, Q, Anti-Inflammatory Agents, Non-Steroidal

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jan 2012Publisher:Hindawi LimitedJournal:The Scientific World Journal, volume 2,012, pages 1-8 (eissn: 1537-744X,

Authors: P. Pérez-Segura; A. Manzano;

doi: 10.1100/2012/327341

pmid: 22649288

pmc: PMC3353298

Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention?

- Summary
- Subjects
- Metrics

Abstract

Colorectal cancer (CRC) is presently one of the most common causes of cancer-related death in our setting and affects a great number of people each year. Screening strategies are commonly used but they do not seem enough to avoid CRC development or prevent completely its mortality. Because of this fact other prevention strategies have gained interest in recent years. Chemoprevention seems to be an attractive option in this setting and several drugs have been studied in this field. This review is focused on salicylates, nonsteroidal anti-inflammatory drugs (NSAIDs) and cycloxygenase-2 inhibitors (COXIBs), whose mechanism of action could be directly related to colon cancer chemoprevention.

Related Organizations

Hospital Clínico San Carlos
Spain
Comunidad de Madrid
Spain

Keywords

Adenoma, Adult, Technology, Sulfonamides, Aspirin, Cyclooxygenase 2 Inhibitors, T, Science, Q, Anti-Inflammatory Agents, Non-Steroidal, R, Review Article, Chemoprevention, Sulindac, Adenomatous Polyposis Coli, Celecoxib, Medicine, Animals, Humans, Pyrazoles, Colorectal Neoplasms, Randomized Controlled Trials as Topic

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	41
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%