Chordoma is a rare malignant intercranial tumor. Cranial base chordomas usually occur extradurally. In the current study, a 44-year-old man with chordoma in cranial base and paranasal sinuses was reported. The patient was managed with combination of surgery and radiotherapy. Surgical phase comprised anterior cranial base osteotomy, removal of lesions, and replacement of osteotomy segment. One-year follow-up showed no evidence of recurrence of lesions. Aggressive surgery with postoperative radiotherapy for treatment of chordoma in the cranial base can be suggested as a proper treatment modality.