Rehabilitation in Latin America was pioneered in the 1940s by orthopedists who envisioned the need for the integration of people with disabilities into society. The objective of this review is to discuss the evolution of rehabilitation in Latin America during the last few decades. This review is divided into the following sections: (1) prehistory, (2) the beginning, (3) common features in different countries, (4) the beginning and consolidation of the specialty, (5) the Latin American Medical Association of Rehabilitation, and (6) journals published by different countries.