Fatal Neonatal Myocarditis Caused by a Recombinant Human Enterovirus-B Variant
Copyright policy )Fatal Neonatal Myocarditis Caused by a Recombinant Human Enterovirus-B Variant
We report a case of fatal myocarditis in a newborn infant who was infected with a human enterovirus detected by throat culture and RT-PCR for viral RNA in plasma. Whole genome sequence analysis revealed the virus to be a genomic chimera that likely arose from recombination between coxsackievirus B3 and two recently identified enteroviruses, EV 86 and EV97.
- Scripps Research Institute United States
- University of California, Los Angeles United States
Male, Recombination, Genetic, Virus Cultivation, Reverse Transcriptase Polymerase Chain Reaction, Molecular Sequence Data, Infant, Newborn, Genome, Viral, Sequence Analysis, DNA, Enterovirus B, Human, Myocarditis, Plasma, Fatal Outcome, Enterovirus Infections, Humans, Pharynx, RNA, Viral
Male, Recombination, Genetic, Virus Cultivation, Reverse Transcriptase Polymerase Chain Reaction, Molecular Sequence Data, Infant, Newborn, Genome, Viral, Sequence Analysis, DNA, Enterovirus B, Human, Myocarditis, Plasma, Fatal Outcome, Enterovirus Infections, Humans, Pharynx, RNA, Viral
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