To report a case of choroidal melanoma metastasizing to contralateral choroid along with systemic metastasis.This is a retrospective study of a case of a 52-year-old man who was found to have a choroidal lesion in the left eye temporal to fovea. The ultrasound and angiographic findings were suggestive of choroidal melanoma, which prompted enucleation of the eye.After approximately 74 months, the patient noticed decreased vision in the contralateral (right) eye. Examination revealed a nonpigmented mass lesion approximately two disk diameters in size superotemporal to fovea, and the patient was found to have multiple secondary tumors in the abdomen and liver.The development of choroidal metastases from a contralateral choroidal melanoma is of ophthalmic interest and seems to be unique.