To describe a case of macular infarction occurring after Enterococcus faecalis endophthalmitis in a patient who had undergone cataract surgery.A 74-year-old woman who underwent uneventful phacoemulsification with intraocular lens implantation developed E. faecalis endophthalmitis on the second postoperative day. Management included repeated intravitreal antibiotic treatment, vitrectomy, and intraocular lens explantation.One week after intraocular inflammation subsided, macular infarction was noted clinically, which was confirmed by fundus fluorescein angiography. Visual acuity did not improve beyond 1/60 by Snellen chart testing.Posterior segment involvement, including optic atrophy, macular hole formation, and tractional retinal detachment, has been reported clinically as a complication of E. faecalis endophthalmitis. Macular infarction could be another sight-threatening complication of endophthalmitis due to E. faecalis.