To report autofluorescence findings for two patients with choroidal melanomas.Records and photographs for two patients with choroidal melanomas were reviewed. Fundus autofluorescence photography was performed using the Heidelberg confocal SLO system (Heidelberg Retina Angiograph; Heidelberg Engineering, Dossenheim, Germany).Both patients had lipofuscin over the melanoma. In Case 1, autofluorescence studies showed a linear streak of autofluorescence and patchy autofluorescence overlying the tumor. In Case 2, autofluorescence photographs showed the presence of small flecklike areas of autofluorescence over the melanoma.Fundus autofluorescence photography is an alternative method for imaging lipofuscin over choroidal lesions.