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Journal of Orthopaedic Trauma
Article . 2012 . Peer-reviewed
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Heterotopic Ossification in Orthopaedic Trauma

Authors: Nauth, Aaron; Giles, Erica; Potter, Benjamin K; Nesti, Leon J; O'Brien, Frederick P; Bosse, Michael J; Anglen, Jeffrey O; +4 Authors

Heterotopic Ossification in Orthopaedic Trauma

Abstract

Heterotopic ossification (HO) can be defined as the pathologic formation of bone in extraskeletal tissues. There has been a substantial amount of recent research on the pathophysiology, prophylaxis, and treatment of HO and traumatic conditions associated with the development of HO. This research has advanced our understanding of this disease and helped to clarify evidence-based approaches to both the prophylaxis and treatment of HO. This article reviews the literature on these topics with a focus on their application in orthopaedic trauma.

Keywords

NSAIDs, surgical treatment, Clinical Sciences, Anti-Inflammatory Agents, Clinical sciences, Ossification, radiation therapy, Models, Biological, Models, Humans, pathophysiology, Biomedical and Clinical Sciences, Radiotherapy, Conformal, traumatic brain injury, Ossification, Heterotopic, Anti-Inflammatory Agents, Non-Steroidal, Biological, spinal cord injury, Osteotomy, Orthopedics, heterotopic ossification, Musculoskeletal, blast injuries, Wounds and Injuries, Heterotopic, prophylaxis, Radiotherapy, Conformal, Non-Steroidal

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    108
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
108
Top 10%
Top 10%
Top 10%
Green
bronze