Colorectal cancer is uncommon during pregnancy. Although there is overlap between symptoms of colon cancer and normal pregnancy, clinicians should be vigilant identifying those at risk and offer colorectal cancer screening when appropriate.Three women in their 30s passed or prolapsed adenomatous tissue per rectum during the second stage of labor. Further evaluation lead to the diagnosis of premalignant lesions or colorectal cancer in each case.Colorectal cancer can present in young women of childbearing age, especially in those with a genetic predisposition. It may present with the prolapse or passage of tissue during vaginal delivery. Appropriate referral and screening are of critical importance for those at risk, especially those with a family history or pertinent physical findings.