Prevalence of childhood constipation has been estimated at 0.7% to 29.6% in the general population worldwide; most children have no obvious etiological factors. The management of constipation is essentially multifactorial and, along with medical treatment, should address the social and psychological issues that may be associated with it.This presentation focuses on the evidence of treatment with pre‐ pro‐ and synbiotics in one of the most prevalent gastrointestinal disorders in children of all ages. Namely, functional constipation.Low fiber intake is associated with constipation and, therefore, every child with or without constipation needs a normal daily fiber intake. The role of extra fiber on constipation requires further evaluation. Clinical guidelines recommend the use of polyethylene glycol (PEG) with or without electrolytes as first‐line maintenance pharmacological treatment for the functional constipation in children rather than dietary interventions alone.There are many different prebiotics and probiotic microorganisms with different effects. Currently, evidence is lacking to support use of any pre‐ or pro‐ or synbiotic strain in the treatment of constipation in children.