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Leukocyte function and nonmalignant leukocyte disorders

Name: Leukocyte function and nonmalignant leukocyte disorders
Creator: Mary C. Dinauer
Keywords: 0301 basic medicine, 03 medical and health sciences, Neutropenia, 0302 clinical medicine, Receptors, Leukocyte-Adhesion, Immunologic Deficiency Syndromes, Infant, Newborn, Leukocytes, Humans, Infant

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1993Publisher:Ovid Technologies (Wolters Kluwer Health)Journal:Current Opinion in Pediatrics, volume 5, pages 80-87 (issn: 1040-8703,

Authors: Mary C. Dinauer;

doi: 10.1097/00008480-199302000-00013

pmid: 8374630

Leukocyte function and nonmalignant leukocyte disorders

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Abstract

This review summarizes recent literature regarding the clinical and molecular features of nonmalignant leukocyte disorders in children. Leukocyte adhesion deficiency and chronic granulomatous disease, two inherited disorders of neutrophil function, continue to be the best-characterized disorders with respect to specific molecular defects. The underlying causes of severe congenital neutropenia and cyclic neutropenia remain elusive. Clinical features of immune-mediated neutropenias and their differential diagnoses are also reviewed.

Related Organizations

DePaul University
United States
Indiana University School of Medicine
United States

Keywords

Neutropenia, Receptors, Leukocyte-Adhesion, Immunologic Deficiency Syndromes, Infant, Newborn, Leukocytes, Humans, Infant, Child, Granulomatous Disease, Chronic

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