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Sarcoidosis and ELISA for Borrelia burgdorferi

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1994Publisher:Southern Medical AssociationJournal:Southern Medical Journal, volume 87, pages 590-591 (issn: 0038-4348,

Authors: Morris Jt; Longfield Rn;

doi: 10.1097/00007611-199406000-00002

pmid: 8202765

Sarcoidosis and ELISA for Borrelia burgdorferi

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Abstract

Lyme disease can be confirmed by detection of IgM and IgG antibodies against the causative pathogen Borrelia burgdorferi. Enzyme-linked immunosorbent assay (ELISA) can be confirmatory within weeks of symptom onset. Sarcoidosis has not previously been reported as one of the disease processes associated with a false-positive ELISA for Lyme disease. In our study, Lyme ELISA was obtained in 25 patients with various degrees of activity of sarcoidosis. ELISA was positive for Lyme disease in only one of these patients. Sarcoidosis may not be one of the diseases that commonly results in a false-positive Lyme ELISA.

Related Organizations

San Antonio Military Medical Center
United States

Keywords

Adult, Male, Lyme Disease, Sarcoidosis, Enzyme-Linked Immunosorbent Assay, Middle Aged, Antibodies, Bacterial, Borrelia burgdorferi Group, Humans, False Positive Reactions, Female, Prospective Studies, Follow-Up Studies

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