
pmid: 3905103
This paper reviews the sequence of histomorphologic changes that occur in and around a fracture site, and discusses recent concepts about the roles of the cells and bone matrical moieties in promoting specific cell transformations during the phases of callus tissue formation and consolidation of the bony cortex. Current knowledge about the roles of autocrine, paracrine, and endocrine polypeptide growth and transforming factors lends new perspectives about this classic problem in bone physiology.
Hematoma, Osteoblasts, Epidermal Growth Factor, Macrophages, Bone Matrix, Osteoclasts, Proteins, Bone and Bones, Fibronectins, Fibroblast Growth Factors, Fractures, Bone, Cartilage, Insulin-Like Growth Factor II, Osteogenesis, Parathyroid Hormone, Bone Morphogenetic Proteins, Animals, Humans, Bone Resorption, Bony Callus
Hematoma, Osteoblasts, Epidermal Growth Factor, Macrophages, Bone Matrix, Osteoclasts, Proteins, Bone and Bones, Fibronectins, Fibroblast Growth Factors, Fractures, Bone, Cartilage, Insulin-Like Growth Factor II, Osteogenesis, Parathyroid Hormone, Bone Morphogenetic Proteins, Animals, Humans, Bone Resorption, Bony Callus
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