
pmid: 7540431
This review examines the development of a new method of screening for Down's syndrome based on the combination of fetal nuchal translucency thickness, maternal age and maternal serum biochemistry at 10-14 weeks of gestation. This method can potentially identify more than 80% of affected fetuses for a false-positive rate of less than 5%.
Chromosome Aberrations, Chromosome Disorders, Chorionic Gonadotropin, Sensitivity and Specificity, Peptide Fragments, Ultrasonography, Prenatal, Pregnancy Trimester, First, Pregnancy, Prenatal Diagnosis, Humans, Pregnancy-Associated Plasma Protein-A, Chorionic Gonadotropin, beta Subunit, Human, Female, Down Syndrome, Neck, Maternal Age
Chromosome Aberrations, Chromosome Disorders, Chorionic Gonadotropin, Sensitivity and Specificity, Peptide Fragments, Ultrasonography, Prenatal, Pregnancy Trimester, First, Pregnancy, Prenatal Diagnosis, Humans, Pregnancy-Associated Plasma Protein-A, Chorionic Gonadotropin, beta Subunit, Human, Female, Down Syndrome, Neck, Maternal Age
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