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Genetic Markers in Familial Narcolepsy

descriptionPublicationkeyboard_double_arrow_right Article 01 May 1991 English Publisher:Oxford University Press (OUP)Journal:Sleep, volume 14, pages 270-271 (issn: 0161-8105, eissn: 1550-9109, Copyright policy )
Authors: O. H. Rundell; William C. Orr; Joe A. Othman;

doi: 10.1093/sleep/14.3.270

pmid: 1896730

Genetic Markers in Familial Narcolepsy

Abstract

We studied three patients in a single family (father and two sons), all with long histories of overwhelming daytime sleepiness, hypnagogic hallucinations and sleep paralysis. Two of the three had a clear history of cataplexy. Multiple sleep latency tests revealed extremely short sleep onset latencies and at least two sleep onset rapid eye movement periods in each patient. Histocompatibility studies were remarkable for negative HLA-DR2 antigens in all three.

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Keywords

Adult, Chromosome Aberrations, Genetic Markers, Male, HLA-D Antigens, Adolescent, Humans, Chromosome Disorders, Genes, Dominant, Narcolepsy, Pedigree

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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 4
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Average
Average
bronze
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