The aim of this study is to explore the use of a quality (Q) factor in digital mammography as a figure-of-merit. Q factors take a reference value into account and can be compared to a theoretical value. They are also intended to summarise the performance of any unit based on a number. The mean glandular dose (MGD)-normalised Q factors were also introduced based on the relationship of the Q factors with MGD. Interestingly, the automatic exposure control exposures did not render the maximum normalised Q factor values as expected, which could indicate the need for further optimisation. It was also noted that the Q factors and the CDMAM-related quality parameters can be confidently predicted for a given MGD which in turn may be compared to the measured values. This might be another way to consider or perform optimisation in digital mammography.