In the face of unpredictable climate patterns, crop growth and yield are becoming increasingly vulnerable, with rice—a staple food crop—being no exception. While much attention has been paid to heat stress and its impact on crops, the effects of cold stress on rice remain underexplored. Cold stress can induce the formation of reactive oxygen species (ROS), impair membrane fluidity, inhibit normal growth, degrade proteins, and disrupt photosynthesis (Xu et al., 2023). To combat cold stress, rice plants have developed a mechanism that includes the accumulation of secondary metabolites like anthocyanins, which are regulated by the MYB-bHLH-WD (MBW) transcription factor complex (Schulz et al., 2015; Xu et al., 2015). Wei et al. (2019) demonstrated that TTG1, a WD40 protein that is part of the MBW complex, plays a critical role in regulating plant pigmentation, vegetative and reproductive growth, and abiotic stress responses, including salt and osmotic stress (Wei et al., 2019). However, how TTG1 responds to cold stress in rice had not been thoroughly studied until recently.